If it is TRULY awesome, I'll add it to the 'HALL OF SYNERGIES!'īut yeah, that is all for me. Leave some super cool synergies YOU'VE found in The Binding of Isaac : Rebirth and IF at all possible, add a picture of the effect it causes. Mom's Knife + Brimstone.Īnd one final one before I sign off here. I had more but I'm an idiot and forgot.Ĥ. Fetus + mutant spider / inner eye / 20/20, Epic Fetus, etc) and Pyromaniac. Any bomb item, (Ipecac + My reflection, Dr. (TRINKETS) Any combination of 2 'X-Worm' trinkets, such as Wiggle worm and round worm.Ģ. (ITEMS) Tammy's Head, Brimstone, Mom's Purse, Tiny Planet. This thread is different, this one is merely talking about cool item synergies and stuff like that.įirst off, I am going to list some of the most amazing synergies I have ever seen in the game.ġ. Bloody lust works differently in Rebirth - Damage is given for taking damage and is persistent for the entire floor. First off, YES I do realize there is another thread(s) for this game! A complete guide to The Binding of Isaac Rebirth and its DLC Afterbirth.